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HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity.
Zheng, Jie; Wang, Chen; Chang, Mi Ra; Devarkar, Swapnil C; Schweibenz, Brandon; Crynen, Gogce C; Garcia-Ordonez, Ruben D; Pascal, Bruce D; Novick, Scott J; Patel, Smita S; Marcotrigiano, Joseph; Griffin, Patrick R.
Affiliation
  • Zheng J; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA. jzheng@scripps.edu.
  • Wang C; Structural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Chang MR; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Devarkar SC; Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 08854, USA.
  • Schweibenz B; Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 08854, USA.
  • Crynen GC; The Center for Computational Biology, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Garcia-Ordonez RD; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Pascal BD; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Novick SJ; Omics Informatics LLC, Honolulu, HI 96813, USA.
  • Patel SS; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Marcotrigiano J; Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 08854, USA.
  • Griffin PR; Structural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. joseph.marcotrigiano@nih.gov.
Nat Commun ; 9(1): 5366, 2018 12 18.
Article in En | MEDLINE | ID: mdl-30560918

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA Caps / RNA, Double-Stranded / Autoimmunity / DEAD Box Protein 58 / Immunity, Innate Type of study: Prognostic_studies Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA Caps / RNA, Double-Stranded / Autoimmunity / DEAD Box Protein 58 / Immunity, Innate Type of study: Prognostic_studies Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Document type: Article Affiliation country: Country of publication: