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Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.
Jacobs, Robert T; Lunde, Christopher S; Freund, Yvonne R; Hernandez, Vincent; Li, Xianfeng; Xia, Yi; Carter, David S; Berry, Pamela W; Halladay, Jason; Rock, Fernando; Stefanakis, Rianna; Easom, Eric; Plattner, Jacob J; Ford, Louise; Johnston, Kelly L; Cook, Darren A N; Clare, Rachel; Cassidy, Andrew; Myhill, Laura; Tyrer, Hayley; Gamble, Joanne; Guimaraes, Ana F; Steven, Andrew; Lenz, Franziska; Ehrens, Alexandra; Frohberger, Stefan J; Koschel, Marianne; Hoerauf, Achim; Hübner, Marc P; McNamara, Case W; Bakowski, Malina A; Turner, Joseph D; Taylor, Mark J; Ward, Stephen A.
Affiliation
  • Jacobs RT; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Lunde CS; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Freund YR; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Hernandez V; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Li X; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Xia Y; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Carter DS; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Berry PW; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Halladay J; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Rock F; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Stefanakis R; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Easom E; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Plattner JJ; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States.
  • Ford L; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Johnston KL; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Cook DAN; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Clare R; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Cassidy A; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Myhill L; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Tyrer H; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Gamble J; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Guimaraes AF; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Steven A; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Lenz F; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany.
  • Ehrens A; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany.
  • Frohberger SJ; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany.
  • Koschel M; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany.
  • Hoerauf A; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany.
  • Hübner MP; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany.
  • McNamara CW; Calibr , 11119 North Torrey Pines Road , Suite 100, La Jolla , California 92037 , United States.
  • Bakowski MA; Calibr , 11119 North Torrey Pines Road , Suite 100, La Jolla , California 92037 , United States.
  • Turner JD; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Taylor MJ; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
  • Ward SA; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
J Med Chem ; 62(5): 2521-2540, 2019 03 14.
Article in En | MEDLINE | ID: mdl-30730745
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Onchocerciasis / Polycyclic Compounds / Wuchereria bancrofti / Elephantiasis, Filarial / Boron / Wolbachia / Diterpenes / Filaricides Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2019 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Onchocerciasis / Polycyclic Compounds / Wuchereria bancrofti / Elephantiasis, Filarial / Boron / Wolbachia / Diterpenes / Filaricides Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2019 Document type: Article Affiliation country: Country of publication: