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Direct quantitation of therapeutic antibodies for pharmacokinetic studies using immuno-purification and intact mass analysis.
Vasicek, Lisa A; Zhu, Xin; Spellman, Daniel S; Bateman, Kevin P.
Affiliation
  • Vasicek LA; Pharmacokinetics, Pharmacodynamics & Drug Metabolism, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Zhu X; Agilent Technologies, 2850 Centerville Rd, Wilmington, DE 19808, USA.
  • Spellman DS; Pharmacokinetics, Pharmacodynamics & Drug Metabolism, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Bateman KP; Pharmacokinetics, Pharmacodynamics & Drug Metabolism, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
Bioanalysis ; 11(3): 203-213, 2019 Feb.
Article in En | MEDLINE | ID: mdl-30734579
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Bioanalysis Year: 2019 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Bioanalysis Year: 2019 Document type: Article Affiliation country: Country of publication: