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Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.
Ling, Shuo-Chien; Dastidar, Somasish Ghosh; Tokunaga, Seiya; Ho, Wan Yun; Lim, Kenneth; Ilieva, Hristelina; Parone, Philippe A; Tyan, Sheue-Houy; Tse, Tsemay M; Chang, Jer-Cherng; Platoshyn, Oleksandr; Bui, Ngoc B; Bui, Anh; Vetto, Anne; Sun, Shuying; McAlonis-Downes, Melissa; Han, Joo Seok; Swing, Debbie; Kapeli, Katannya; Yeo, Gene W; Tessarollo, Lino; Marsala, Martin; Shaw, Christopher E; Tucker-Kellogg, Greg; La Spada, Albert R; Lagier-Tourenne, Clotilde; Da Cruz, Sandrine; Cleveland, Don W.
Affiliation
  • Ling SC; Ludwig Institute for Cancer Research, University of California, San Diego, San Diego, United States.
  • Dastidar SG; Department of Cellular and Molecular Medicine, University of California, San Diego, San Diego, United States.
  • Tokunaga S; Department of Neurosciences, University of California, San Diego, San Diego, United States.
  • Ho WY; Department of Physiology, National University of Singapore, Singapore, Singapore.
  • Lim K; Neurobiology/Ageing Programme, National University of Singapore, Singapore, Singapore.
  • Ilieva H; Program in Neuroscience and Behavior Disorders, Duke-NUS Medical School, Singapore, Singapore.
  • Parone PA; Sanford Consortium for Regenerative Medicine, University of California, San Diego, San Diego, United States.
  • Tyan SH; Ludwig Institute for Cancer Research, University of California, San Diego, San Diego, United States.
  • Tse TM; Department of Physiology, National University of Singapore, Singapore, Singapore.
  • Chang JC; Department of Physiology, National University of Singapore, Singapore, Singapore.
  • Platoshyn O; Ludwig Institute for Cancer Research, University of California, San Diego, San Diego, United States.
  • Bui NB; Department of Cellular and Molecular Medicine, University of California, San Diego, San Diego, United States.
  • Bui A; Ludwig Institute for Cancer Research, University of California, San Diego, San Diego, United States.
  • Vetto A; Department of Cellular and Molecular Medicine, University of California, San Diego, San Diego, United States.
  • Sun S; Department of Neurosciences, University of California, San Diego, San Diego, United States.
  • McAlonis-Downes M; Department of Medicine, National University of Singapore, Singapore, Singapore.
  • Han JS; Department of Physiology, National University of Singapore, Singapore, Singapore.
  • Swing D; Ludwig Institute for Cancer Research, University of California, San Diego, San Diego, United States.
  • Kapeli K; Department of Anesthesiology, University of California, San Diego, San Diego, United States.
  • Yeo GW; Ludwig Institute for Cancer Research, University of California, San Diego, San Diego, United States.
  • Tessarollo L; Ludwig Institute for Cancer Research, University of California, San Diego, San Diego, United States.
  • Marsala M; Ludwig Institute for Cancer Research, University of California, San Diego, San Diego, United States.
  • Shaw CE; Ludwig Institute for Cancer Research, University of California, San Diego, San Diego, United States.
  • Tucker-Kellogg G; Department of Cellular and Molecular Medicine, University of California, San Diego, San Diego, United States.
  • La Spada AR; Ludwig Institute for Cancer Research, University of California, San Diego, San Diego, United States.
  • Lagier-Tourenne C; Department of Cellular and Molecular Medicine, University of California, San Diego, San Diego, United States.
  • Da Cruz S; Ludwig Institute for Cancer Research, University of California, San Diego, San Diego, United States.
  • Cleveland DW; Department of Cellular and Molecular Medicine, University of California, San Diego, San Diego, United States.
Elife ; 82019 02 12.
Article in En | MEDLINE | ID: mdl-30747709
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / RNA / RNA-Binding Protein FUS / Homeostasis / Lysosomes Limits: Animals / Humans Language: En Journal: Elife Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / RNA / RNA-Binding Protein FUS / Homeostasis / Lysosomes Limits: Animals / Humans Language: En Journal: Elife Year: 2019 Document type: Article Affiliation country: Country of publication: