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Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary.
Akino, Nana; Wada-Hiraike, Osamu; Isono, Wataru; Terao, Hiromi; Honjo, Harunori; Miyamoto, Yuichiro; Tanikawa, Michihiro; Sone, Kenbun; Hirano, Mana; Harada, Miyuki; Hirata, Tetsuya; Hirota, Yasushi; Koga, Kaori; Oda, Katsutoshi; Fujii, Tomoyuki; Osuga, Yutaka.
Affiliation
  • Akino N; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Wada-Hiraike O; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan. osamuwh-tky@umin.ac.jp.
  • Isono W; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Terao H; Department of Obstetrics and Gynecology, Mizonokuchi Hospital, Teikyo University, Kawasaki, 2138507, Japan.
  • Honjo H; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Miyamoto Y; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Tanikawa M; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Sone K; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Hirano M; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Harada M; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Hirata T; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Hirota Y; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Koga K; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Oda K; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Fujii T; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
  • Osuga Y; Department of Obstetrics and Gynecology, Graduate school of Medicine, The University of Tokyo, Tokyo, 1138655, Japan.
Reprod Biol Endocrinol ; 17(1): 23, 2019 Feb 13.
Article in En | MEDLINE | ID: mdl-30760288
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Oxidative Stress / NF-E2-Related Factor 2 / Dimethyl Fumarate / Kelch-Like ECH-Associated Protein 1 / Infertility, Female Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Reprod Biol Endocrinol Journal subject: ENDOCRINOLOGIA / MEDICINA REPRODUTIVA Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Oxidative Stress / NF-E2-Related Factor 2 / Dimethyl Fumarate / Kelch-Like ECH-Associated Protein 1 / Infertility, Female Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Reprod Biol Endocrinol Journal subject: ENDOCRINOLOGIA / MEDICINA REPRODUTIVA Year: 2019 Document type: Article Affiliation country: Country of publication: