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Factory and construction work is associated with an increased risk of severe lumbar spinal stenosis on MRI: A case control analysis within the wakayama spine study.
Ishimoto, Yuyu; Cooper, Cyrus; Ntani, Georgia; Yamada, Hiroshi; Hashizume, Hiroshi; Nagata, Keiji; Muraki, Shigeyuki; Tanaka, Sakae; Yoshimura, Noriko; Yoshida, Munehito; Walker-Bone, Karen.
Affiliation
  • Ishimoto Y; MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, Hampshire, United Kingdom.
  • Cooper C; Orthopedic surgery, Wakayama Medical University, Wakayama city, Wakayama prefecture, Japan.
  • Ntani G; MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, Hampshire, United Kingdom.
  • Yamada H; Arthritis Research UK/MRC Centre for Musculoskeletal Work and Health, Southampton General Hospital, Southampton, Hampshire, United Kingdom.
  • Hashizume H; MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, Hampshire, United Kingdom.
  • Nagata K; Arthritis Research UK/MRC Centre for Musculoskeletal Work and Health, Southampton General Hospital, Southampton, Hampshire, United Kingdom.
  • Muraki S; Orthopedic surgery, Wakayama Medical University, Wakayama city, Wakayama prefecture, Japan.
  • Tanaka S; Orthopedic surgery, Wakayama Medical University, Wakayama city, Wakayama prefecture, Japan.
  • Yoshimura N; Orthopedic surgery, Wakayama Medical University, Wakayama city, Wakayama prefecture, Japan.
  • Yoshida M; Faculty of Medicine, Department of Preventive Medicine for Locomotive Organ Disorders, 22nd Century Medical & Research Center, University of Tokyo, Tokyo, Japan.
  • Walker-Bone K; Department of Orthopedic Surgery, Sensory and Motor System Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Am J Ind Med ; 62(5): 430-438, 2019 05.
Article in En | MEDLINE | ID: mdl-30762243
BACKGROUND: To explore the association of MRI-diagnosed severe lumbar spinal stenosis with occupation. METHODS: Occupational data were collected by questionnaire and all participants underwent spine MRI scans using the same protocol. Central lumbar spinal stenosis (LSS) was graded qualitatively. Those with severe LSS (>two-thirds narrowing) were compared with the controls with lesser degrees of stenosis or no stenosis. RESULTS: Data were available for 722 subjects, mean age 70.1 years. 239 (33%) cases with severe LSS were identified. Factory/construction workers had an almost four-fold increased risk of severe LSS after adjustment for age, sex, smoking, and walking speed amongst those aged <75 years (OR 3.97, 95%CI 1.46-10.85). Severe LSS was also associated with squatting ≥1 h/day (OR 1.76, 95%CI 1.01-3.07) but this association became non-significant after adjustment. CONCLUSION: Further research is needed but this study adds more evidence that occupational factors are associated with an increased risk and/or severity of degenerative disease of the lumbar spine.
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Stenosis / Occupational Exposure / Lumbar Vertebrae / Occupational Diseases Type of study: Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Am J Ind Med Year: 2019 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Stenosis / Occupational Exposure / Lumbar Vertebrae / Occupational Diseases Type of study: Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Am J Ind Med Year: 2019 Document type: Article Affiliation country: Country of publication: