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Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Yu, Zhenlong; Jv, Yanan; Cai, Lu; Tian, Xiangge; Huo, Xiaokui; Wang, Chao; Zhang, Baojing; Sun, ChengPeng; Ning, Jing; Feng, Lei; Zhang, Houli; Ma, Xiaochi.
Affiliation
  • Yu Z; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Jv Y; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Cai L; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Tian X; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Huo X; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Wang C; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Zhang B; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Sun C; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Ning J; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Feng L; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Zhang H; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China. Electronic address: zhanghouli@dmu.edu.cn.
  • Ma X; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China. Electronic address: maxc1978@163.com.
Toxicol Appl Pharmacol ; 371: 63-73, 2019 05 15.
Article in En | MEDLINE | ID: mdl-30953615
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HSP90 Heat-Shock Proteins / Mitogen-Activated Protein Kinases / Xanthones / Proto-Oncogene Proteins c-akt / Hepatic Stellate Cells / Phosphatidylinositol 3-Kinase / Liver / Liver Cirrhosis, Experimental Limits: Animals / Humans / Male Language: En Journal: Toxicol Appl Pharmacol Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HSP90 Heat-Shock Proteins / Mitogen-Activated Protein Kinases / Xanthones / Proto-Oncogene Proteins c-akt / Hepatic Stellate Cells / Phosphatidylinositol 3-Kinase / Liver / Liver Cirrhosis, Experimental Limits: Animals / Humans / Male Language: En Journal: Toxicol Appl Pharmacol Year: 2019 Document type: Article Affiliation country: Country of publication: