Your browser doesn't support javascript.
loading
Biodegradable antioxidant chitosan films useful as an anti-aging skin mask.
Afonso, C R; Hirano, R S; Gaspar, A L; Chagas, E G L; Carvalho, R A; Silva, F V; Leonardi, G R; Lopes, P S; Silva, C F; Yoshida, C M P.
Affiliation
  • Afonso CR; UNIFESP - Federal São Paulo University, Institute of Environmental, Chemical and Pharmaceutical Science, SP, Brazil.
  • Hirano RS; UNIFESP - Federal São Paulo University, Institute of Environmental, Chemical and Pharmaceutical Science, SP, Brazil.
  • Gaspar AL; UNIFESP - Federal São Paulo University, Institute of Environmental, Chemical and Pharmaceutical Science, SP, Brazil.
  • Chagas EGL; USP - University of São Paulo, Faculty of Animal Science and Food Engineering, SP, Brazil.
  • Carvalho RA; USP - University of São Paulo, Faculty of Animal Science and Food Engineering, SP, Brazil.
  • Silva FV; UNICAMP - State University of Campinas, School of Chemical Engineering, SP, Brazil.
  • Leonardi GR; UNICAMP - State University of Campinas, Pharmacy Faculty, SP, Brazil.
  • Lopes PS; UNIFESP - Federal São Paulo University, Institute of Environmental, Chemical and Pharmaceutical Science, SP, Brazil.
  • Silva CF; UNIFESP - Federal São Paulo University, Institute of Environmental, Chemical and Pharmaceutical Science, SP, Brazil. Electronic address: cfsilva@unifesp.br.
  • Yoshida CMP; UNIFESP - Federal São Paulo University, Institute of Environmental, Chemical and Pharmaceutical Science, SP, Brazil.
Int J Biol Macromol ; 132: 1262-1273, 2019 Jul 01.
Article in En | MEDLINE | ID: mdl-30980874
ABSTRACT
Cosmetics, personal care and biomedical products obtained by bio-based polymers and natural bioactive compounds are a new growing market. The ecological awareness is changing consumers' demands, causing consumers to look for more sustainable options, with a reduced environmental impact. The innovation of this work was to develop a natural polymer matrix (chitosan) entrapping antioxidant actives compounds such as annatto (Bixa Orellana L.) and vitamin C with potential application as sustainable anti-aging skin mask treatment. Films of chitosan (Ch) and reacetylated chitosan (RCh), exhibiting different degrees of acetylation (DA = 13.3 and 33.9%, respectively), were produced. The formulations of active films of chitosan (BCh) and reacetylated chitosan (BRCh) were 1% (w/w) of chitosan, 1% (w/w) of annatto powder, 5% (w/w) of vitamin C and 1% (w/w) of glycerol (as plasticizer). Reacetylated chitosan films (DA = 33.9%) presented higher water affinity than chitosan films (DA = 13.3%). The elongation of RCh and BRCh increased and the resistance decreased, as compared to Ch and BCh. The antioxidants compounds (annatto and vitamin C) of BRCh films released faster than BCh films. Thus, the BRCh films showed potential application as an anti-aging skin mask.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin / Aging / Drug Carriers / Cosmetics / Chitosan / Antioxidants Limits: Humans Language: En Journal: Int J Biol Macromol Year: 2019 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin / Aging / Drug Carriers / Cosmetics / Chitosan / Antioxidants Limits: Humans Language: En Journal: Int J Biol Macromol Year: 2019 Document type: Article Affiliation country: