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Gene Editing-Mediated Disruption of Epidermolytic Ichthyosis-Associated KRT10 Alleles Restores Filament Stability in Keratinocytes.
March, Oliver P; Lettner, Thomas; Klausegger, Alfred; Ablinger, Michael; Kocher, Thomas; Hainzl, Stefan; Peking, Patricia; Lackner, Nina; Rajan, Neil; Hofbauer, Josefina Piñón; Guttmann-Gruber, Christina; Bygum, Anette; Koller, Ulrich; Reichelt, Julia.
Affiliation
  • March OP; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria; Institute of Cellular Medicine, Framlington Place, Newcastle University, Newcastle, United Kingdom.
  • Lettner T; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria.
  • Klausegger A; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria.
  • Ablinger M; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria.
  • Kocher T; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria.
  • Hainzl S; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria.
  • Peking P; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria; Experimental and Clinical Cell Therapy Institute, Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS),
  • Lackner N; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria.
  • Rajan N; Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom.
  • Hofbauer JP; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria.
  • Guttmann-Gruber C; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria.
  • Bygum A; Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark.
  • Koller U; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria.
  • Reichelt J; EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Austria. Electronic address: j.reichelt@salk.at.
J Invest Dermatol ; 139(8): 1699-1710.e6, 2019 08.
Article in En | MEDLINE | ID: mdl-30998984
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin / Intermediate Filaments / Hyperkeratosis, Epidermolytic / Keratin-10 / Gene Editing Type of study: Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Journal: J Invest Dermatol Year: 2019 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin / Intermediate Filaments / Hyperkeratosis, Epidermolytic / Keratin-10 / Gene Editing Type of study: Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Journal: J Invest Dermatol Year: 2019 Document type: Article Affiliation country: