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CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target genes.
Datsomor, Alex K; Zic, Nikola; Li, Keshuai; Olsen, Rolf E; Jin, Yang; Vik, Jon Olav; Edvardsen, Rolf B; Grammes, Fabian; Wargelius, Anna; Winge, Per.
Affiliation
  • Datsomor AK; Norwegian University of Science and Technology, Department of Biology, Trondheim, N-7491, Norway.
  • Zic N; Norwegian University of Science and Technology, Department of Biology, Trondheim, N-7491, Norway.
  • Li K; Norwegian University of Science and Technology, Department of Biology, Trondheim, N-7491, Norway.
  • Olsen RE; BioMar AS, Trondheim, Norway.
  • Jin Y; Norwegian University of Science and Technology, Department of Biology, Trondheim, N-7491, Norway.
  • Vik JO; Institute of Marine Research, Bergen, N-5817, Norway.
  • Edvardsen RB; Norwegian University of Life Sciences, Department of Animal and Aquacultural Sciences, N-1432, Ås, Norway.
  • Grammes F; Norwegian University of Life Sciences, Department of Animal and Aquacultural Sciences, N-1432, Ås, Norway.
  • Wargelius A; Institute of Marine Research, Bergen, N-5817, Norway.
  • Winge P; Norwegian University of Life Sciences, Department of Animal and Aquacultural Sciences, N-1432, Ås, Norway.
Sci Rep ; 9(1): 7533, 2019 05 17.
Article in En | MEDLINE | ID: mdl-31101849

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Salmo salar / Sterol Regulatory Element Binding Protein 1 / Fatty Acid Synthases / Fatty Acids, Unsaturated / Fatty Acid Elongases Limits: Animals Language: En Journal: Sci Rep Year: 2019 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Salmo salar / Sterol Regulatory Element Binding Protein 1 / Fatty Acid Synthases / Fatty Acids, Unsaturated / Fatty Acid Elongases Limits: Animals Language: En Journal: Sci Rep Year: 2019 Document type: Article Affiliation country: Country of publication: