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Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial.
Vincent, Jean-Louis; Francois, Bruno; Zabolotskikh, Igor; Daga, Mradul Kumar; Lascarrou, Jean-Baptiste; Kirov, Mikhail Y; Pettilä, Ville; Wittebole, Xavier; Meziani, Ferhat; Mercier, Emmanuelle; Lobo, Suzana M; Barie, Philip S; Crowther, Mark; Esmon, Charles T; Fareed, Jawed; Gando, Satoshi; Gorelick, Kenneth J; Levi, Marcel; Mira, Jean-Paul; Opal, Steven M; Parrillo, Joseph; Russell, James A; Saito, Hidehiko; Tsuruta, Kazuhisa; Sakai, Takumi; Fineberg, David.
Affiliation
  • Vincent JL; Department of Intensive Care, Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium.
  • Francois B; ICU Department, Inserm CIC-1435 & UMR-1092, CHU Dupuytren, Limoges, France.
  • Zabolotskikh I; Department of Anesthesiology, Intensive Care and Transfusiology, Kuban State Medical University, Krasnodar, Russia.
  • Daga MK; Department of Medicine, Maulana Azad Medical College and associated hospitals, New Delhi, India.
  • Lascarrou JB; Centre Hospitalier Universitaire de Nantes, Nantes, France.
  • Kirov MY; Department of Anesthesiology and Intensive Care Medicine, Northern State Medical University, Arkhangelsk, Russia.
  • Pettilä V; Department of Anesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Wittebole X; Department of Critical Care Medicine, St Luc University Hospital, Université Catholique de Louvain, Brussels, Belgium.
  • Meziani F; Faculté de Médecine, Université de Strasbourg (UNISTRA), Hôpitaux Universitaires de Strasbourg, Service de Réanimation, Nouvel Hôpital Civil, Strasbourg, France.
  • Mercier E; Médecine Intensive Réanimation, CHRU de Tours, Tours, France.
  • Lobo SM; Intensive Care Division, Hospital de Base, São José do Rio Preto, SP, Brazil.
  • Barie PS; Departments of Surgery and Medicine, Weill Cornell Medicine, New York, New York.
  • Crowther M; Department of Medicine, McMaster University and St Joseph's Hospital, Hamilton, Canada.
  • Esmon CT; Coagulation Biology Laboratory, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma.
  • Fareed J; Pathology and Pharmacology, Loyola University Medical Center, Maywood, Illinois.
  • Gando S; Acute and Critical Care Center, Sapporo Higashi Tokushukai Hospital, Sapporo, Japan.
  • Gorelick KJ; Zymo Consulting Group LLC, Newtown Square, Massachusetts.
  • Levi M; Department of Medicine, University College London Hospitals and Cardiometabolic Programme-NIHR UCLH/UCL BRC, London, United Kingdom.
  • Mira JP; Universite´Paris Descartes, Sorbonne Paris Cite´, Faculte´ de Me´-decine Cochin University Hospital, AP-HP, Paris, France.
  • Opal SM; Division of Infectious Diseases, Rhode Island Hospital, Providence, Rhode Island.
  • Parrillo J; Department of Medicine, New Jersey Medical School of Rutgers University, Hackenseck.
  • Russell JA; Heart and Vascular Hospital, Hackensack University Medical Center, Hackensack, New Jersey.
  • Saito H; Department of Medicine, Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, Canada.
  • Tsuruta K; National Hospital Organization, Nagoya Medical Center, Nagoya, Japan.
  • Sakai T; Asahi-Kasei Pharma Corporation, Tokyo, Japan.
  • Fineberg D; Asahi-Kasei Pharma Corporation, Tokyo, Japan.
JAMA ; 321(20): 1993-2002, 2019 05 28.
Article in En | MEDLINE | ID: mdl-31104069
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Coagulation Disorders / Thrombomodulin / Sepsis / Anticoagulants Type of study: Clinical_trials / Etiology_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: JAMA Year: 2019 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Coagulation Disorders / Thrombomodulin / Sepsis / Anticoagulants Type of study: Clinical_trials / Etiology_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: JAMA Year: 2019 Document type: Article Affiliation country: