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NIPSNAP Beacons in Mitophagy.
Mukherjee, Rukmini; Dikic, Ivan.
Affiliation
  • Mukherjee R; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; Buchmann Institute for Molecular Life Sciences, Goethe University, Max-von-Laue-Str. 15, 60438 Frankfurt am Main, Germany.
  • Dikic I; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; Buchmann Institute for Molecular Life Sciences, Goethe University, Max-von-Laue-Str. 15, 60438 Frankfurt am Main, Germany. Electronic address: dikic@biochem2.uni-frankfurt.de.
Dev Cell ; 49(4): 503-505, 2019 05 20.
Article in En | MEDLINE | ID: mdl-31112696
ABSTRACT
In healthy cells, dysfunctional mitochondria are removed by selective autophagy (mitophagy), impairment of which causes disease. In this issue of Developmental Cell, Princely Abudu et al. (2019) delineate the function of NIPSNAP1 and NIPSNAP2 in recruiting mitophagy receptors to depolarized mitochondria, highlighting their importance in the zebrafish brain.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Mitophagy Language: En Journal: Dev Cell Journal subject: EMBRIOLOGIA Year: 2019 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Mitophagy Language: En Journal: Dev Cell Journal subject: EMBRIOLOGIA Year: 2019 Document type: Article Affiliation country: