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Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.
Canela, Andres; Maman, Yaakov; Huang, Shar-Yin N; Wutz, Gordana; Tang, Wen; Zagnoli-Vieira, Guido; Callen, Elsa; Wong, Nancy; Day, Amanda; Peters, Jan-Michael; Caldecott, Keith W; Pommier, Yves; Nussenzweig, André.
Affiliation
  • Canela A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA; The Hakubi Center for Advanced Research and Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
  • Maman Y; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Huang SN; Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, NIH, Bethesda, MD, USA.
  • Wutz G; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria.
  • Tang W; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria.
  • Zagnoli-Vieira G; Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton BN1 9RQ, UK.
  • Callen E; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Wong N; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Day A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Peters JM; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria.
  • Caldecott KW; Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton BN1 9RQ, UK; Department of Genome Dynamics, Institute of Molecular Genetics of the Czech Academy of Sciences, 142 20 Prague, 4, Czech Republic.
  • Pommier Y; Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, NIH, Bethesda, MD, USA.
  • Nussenzweig A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA. Electronic address: andre_nussenzweig@nih.gov.
Mol Cell ; 75(2): 252-266.e8, 2019 07 25.
Article in En | MEDLINE | ID: mdl-31202577
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / DNA Topoisomerases, Type II / Multiprotein Complexes / DNA Breaks, Double-Stranded / Poly-ADP-Ribose Binding Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2019 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / DNA Topoisomerases, Type II / Multiprotein Complexes / DNA Breaks, Double-Stranded / Poly-ADP-Ribose Binding Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2019 Document type: Article Affiliation country: