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Discovery of Imidazoisoindole Derivatives as Highly Potent and Orally Active Indoleamine-2,3-dioxygenase Inhibitors.
Tu, Wangyang; Yang, Fanglong; Xu, Guoji; Chi, Jiangtao; Liu, Zhiwei; Peng, Wei; Hu, Bing; Zhang, Lei; Wan, Hong; Yu, Nan; Jin, Fangfang; Hu, Qiyue; Zhang, Lianshan; He, Feng; Tao, Weikang.
Affiliation
  • Tu W; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Yang F; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Xu G; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Chi J; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Liu Z; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Peng W; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Hu B; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Zhang L; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Wan H; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Yu N; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Jin F; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Hu Q; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Zhang L; Jiangsu Hengrui Medicine Co., Ltd., Lianyungang, Jiangsu 222047, China.
  • He F; Shanghai Hengrui Pharmaceutical Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.
  • Tao W; Chengdu Suncadia Medicine Co., Ltd., 88 South Keyuan Road, Chengdu, Sichuan 610000, China.
ACS Med Chem Lett ; 10(6): 949-953, 2019 Jun 13.
Article in En | MEDLINE | ID: mdl-31223453
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2019 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2019 Document type: Article Affiliation country: Country of publication: