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Isorhynchophylline exerts antidepressant-like effects in mice via modulating neuroinflammation and neurotrophins: involvement of the PI3K/Akt/GSK-3ß signaling pathway.
Xian, Yan-Fang; Ip, Siu-Po; Li, Hui-Qin; Qu, Chang; Su, Zi-Ren; Chen, Jian-Nan; Lin, Zhi-Xiu.
Affiliation
  • Xian YF; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Ip SP; Brain Research Center, School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Li HQ; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Qu C; Brain Research Center, School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Su ZR; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Chen JN; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Lin ZX; Guangdong Provincial Key Laboratory of New Drug Development and Research of Chinese Medicine, Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
FASEB J ; 33(9): 10393-10408, 2019 09.
Article in En | MEDLINE | ID: mdl-31233346
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Phosphatidylinositol 3-Kinases / Depression / Proto-Oncogene Proteins c-akt / Glycogen Synthase Kinase 3 beta / Oxindoles / Inflammation Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Phosphatidylinositol 3-Kinases / Depression / Proto-Oncogene Proteins c-akt / Glycogen Synthase Kinase 3 beta / Oxindoles / Inflammation Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2019 Document type: Article Affiliation country: Country of publication: