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Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Zhu, Xing; Clarke, Ryan; Puppala, Anupama K; Chittori, Sagar; Merk, Alan; Merrill, Bradley J; Simonovic, Miljan; Subramaniam, Sriram.
Affiliation
  • Zhu X; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Clarke R; University of British Columbia, Vancouver, British Columbia, Canada.
  • Puppala AK; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL, USA.
  • Chittori S; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL, USA.
  • Merk A; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Merrill BJ; University of British Columbia, Vancouver, British Columbia, Canada.
  • Simonovic M; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Subramaniam S; Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Nat Struct Mol Biol ; 26(8): 679-685, 2019 08.
Article in En | MEDLINE | ID: mdl-31285607
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / CRISPR-Cas Systems / CRISPR-Associated Protein 9 Language: En Journal: Nat Struct Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / CRISPR-Cas Systems / CRISPR-Associated Protein 9 Language: En Journal: Nat Struct Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2019 Document type: Article Affiliation country: Country of publication: