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A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation.
Yoder, Nicholas C; Bai, Chen; Tavares, Daniel; Widdison, Wayne C; Whiteman, Kathleen R; Wilhelm, Alan; Wilhelm, Sharon D; McShea, Molly A; Maloney, Erin K; Ab, Olga; Wang, Lintao; Jin, Shan; Erickson, Hans K; Keating, Thomas A; Lambert, John M.
Mol Pharm ; 16(9): 3926-3937, 2019 09 03.
Article in En | MEDLINE | ID: mdl-31287952
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uterine Cervical Neoplasms / Immunoconjugates / Cysteine / Lysine / Maytansine / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2019 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uterine Cervical Neoplasms / Immunoconjugates / Cysteine / Lysine / Maytansine / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2019 Document type: Article Country of publication: