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The triphenylmethane dye brilliant blue G is only moderately effective at inhibiting amyloid formation by human amylin or at disaggregating amylin amyloid fibrils, but interferes with amyloid assays; Implications for inhibitor design.
Akter, Rehana; Zhyvoloup, Alexander; Zheng, Bingqian; Bhatia, Surita R; Raleigh, Daniel P.
Affiliation
  • Akter R; Department of Chemistry, Stony Brook University, Stony Brook, NY, United States of America.
  • Zhyvoloup A; Institute of Structural and Molecular Biology, University College London, Gower Street, London, United Kingdom.
  • Zheng B; Department of Chemistry, Stony Brook University, Stony Brook, NY, United States of America.
  • Bhatia SR; Department of Chemistry, Stony Brook University, Stony Brook, NY, United States of America.
  • Raleigh DP; Department of Chemistry, Stony Brook University, Stony Brook, NY, United States of America.
PLoS One ; 14(8): e0219130, 2019.
Article in En | MEDLINE | ID: mdl-31404073
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rosaniline Dyes / Trityl Compounds / Biological Assay / Drug Design / Islet Amyloid Polypeptide / Amylin Receptor Agonists / Amyloid Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rosaniline Dyes / Trityl Compounds / Biological Assay / Drug Design / Islet Amyloid Polypeptide / Amylin Receptor Agonists / Amyloid Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article Affiliation country: Country of publication: