Total synthesis of wikstrol A and wikstrol B.
Org Biomol Chem
; 17(35): 8206-8213, 2019 09 21.
Article
in En
| MEDLINE
| ID: mdl-31429850
ABSTRACT
The first total synthesis of wikstrol A and wikstrol B was achieved by employing aldol reaction, Sharpless asymmetric dihydroxylation, regioselective iodination, Sonogashira coupling, and rhodium-catalyzed oxidative coupling as key steps. The structure of the key intermediate for wikstrol A was confirmed via its derivative by single-crystal X-ray analysis.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Org Biomol Chem
Journal subject:
BIOQUIMICA
/
QUIMICA
Year:
2019
Document type:
Article