Dietary supplementation of potassium sorbate, hydrated sodium calcium almuniosilicate and methionine enhances growth, antioxidant status and immunity in growing rabbits exposed to aflatoxin B1 in the diet.
J Anim Physiol Anim Nutr (Berl)
; 104(1): 196-203, 2020 Jan.
Article
in En
| MEDLINE
| ID: mdl-31701584
The present experiment was conducted to evaluate the effect of dietary supplementation with some feed additives (potassium sorbate; Sor, hydrated sodium calcium almuniosilicate; Hsc and L-methionine; L-M) against aflatoxin B1 (AF) toxicity in rabbits. A total of 72 growing rabbits (5-week-old) were distributed into six equal groups (4 replicates with 3 rabbits each). The experimental groups are as follows: control group, AF group (supplemented with AF 0.3 mg/kg diet), AF + Sor group (AF 0.3 mg/kg diet + Sor 2 g/kg diet), AF + Hsc group (AF 0.3 mg/kg diet + Hsc 5 g/kg diet), AF + L-M group (AF 0.3 mg/kg diet + L-M 8 g/kg diet) and AF + Mix group (AF 0.3 mg/kg diet + 2 Sor + 5 Hsc + 8 L-M g/kg diet). Live body weight and weight gain at 13 weeks of age were significantly reduced by AF. Feed intake at 13 weeks of age was decreased in AF, AF + Hsc and AF + Mix compared to the control. AF, AF + Hsc and AF + Mix showed the lowest total antioxidant capacity compared to the control. The highest level of reactive oxygen species and 8-Hydroxy-2-desoxyguanosine was observed in AF group. Using of other supplements with AF increased immunoglobulinM than AF alone. In conclusion, dietary supplementation of Sor, L-M, Hsc or their mixture was effective in reducing the adverse effects of AF on performance, antioxidant and immune status of rabbits with more better improvement obtained by Sor or L-M separately.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rabbits
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Sorbic Acid
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Aflatoxin B1
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Aluminum Silicates
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Methionine
Limits:
Animals
Language:
En
Journal:
J Anim Physiol Anim Nutr (Berl)
Journal subject:
CIENCIAS DA NUTRICAO
/
FISIOLOGIA
/
MEDICINA VETERINARIA
Year:
2020
Document type:
Article
Affiliation country:
Country of publication: