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Machine Learning for Prioritization of Thermostabilizing Mutations for G-Protein Coupled Receptors.
Muk, Sanychen; Ghosh, Soumadwip; Achuthan, Srisairam; Chen, Xiaomin; Yao, XiaoJie; Sandhu, Manbir; Griffor, Matthew C; Fennell, Kimberly F; Che, Ye; Shanmugasundaram, Veerabahu; Qiu, Xiayang; Tate, Christopher G; Vaidehi, Nagarajan.
Affiliation
  • Muk S; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California.
  • Ghosh S; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California.
  • Achuthan S; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California.
  • Chen X; Discovery Sciences, Pfizer, Groton, Connecticut.
  • Yao X; Discovery Sciences, Pfizer, Groton, Connecticut.
  • Sandhu M; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California.
  • Griffor MC; Discovery Sciences, Pfizer, Groton, Connecticut.
  • Fennell KF; Discovery Sciences, Pfizer, Groton, Connecticut.
  • Che Y; Discovery Sciences, Pfizer, Groton, Connecticut.
  • Shanmugasundaram V; Discovery Sciences, Pfizer, Groton, Connecticut.
  • Qiu X; Discovery Sciences, Pfizer, Groton, Connecticut.
  • Tate CG; MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
  • Vaidehi N; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California. Electronic address: nvaidehi@coh.org.
Biophys J ; 117(11): 2228-2239, 2019 12 03.
Article in En | MEDLINE | ID: mdl-31703801
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sequence Analysis / Receptor, Anaphylatoxin C5a / Molecular Dynamics Simulation / Mutation Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biophys J Year: 2019 Document type: Article Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sequence Analysis / Receptor, Anaphylatoxin C5a / Molecular Dynamics Simulation / Mutation Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biophys J Year: 2019 Document type: Article Country of publication: