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HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma.
Courtney, Kevin D; Ma, Yuanqing; Diaz de Leon, Alberto; Christie, Alana; Xie, Zhiqun; Woolford, Layton; Singla, Nirmish; Joyce, Allison; Hill, Haley; Madhuranthakam, Ananth J; Yuan, Qing; Xi, Yin; Zhang, Yue; Chang, Jenny; Fatunde, Oluwatomilade; Arriaga, Yull; Frankel, Arthur E; Kalva, Sanjeeva; Zhang, Song; McKenzie, Tiffani; Reig Torras, Oscar; Figlin, Robert A; Rini, Brian I; McKay, Renée M; Kapur, Payal; Wang, Tao; Pedrosa, Ivan; Brugarolas, James.
Affiliation
  • Courtney KD; Hematology-Oncology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Ma Y; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Diaz de Leon A; Hematology-Oncology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Christie A; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Xie Z; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Woolford L; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Singla N; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Joyce A; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Hill H; Department of Population and Data Sciences, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Madhuranthakam AJ; Hematology-Oncology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Yuan Q; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Xi Y; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Zhang Y; Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Chang J; Hematology-Oncology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Fatunde O; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Arriaga Y; Hematology-Oncology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Frankel AE; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Kalva S; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Zhang S; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • McKenzie T; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Reig Torras O; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Figlin RA; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Rini BI; Department of Population and Data Sciences, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • McKay RM; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Kapur P; Hematology-Oncology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Wang T; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Pedrosa I; Hematology-Oncology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Brugarolas J; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
Clin Cancer Res ; 26(4): 793-803, 2020 02 15.
Article in En | MEDLINE | ID: mdl-31727677
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfones / Carcinoma, Renal Cell / Basic Helix-Loop-Helix Transcription Factors / Indans / Kidney Neoplasms Type of study: Clinical_trials / Observational_studies / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2020 Document type: Article Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfones / Carcinoma, Renal Cell / Basic Helix-Loop-Helix Transcription Factors / Indans / Kidney Neoplasms Type of study: Clinical_trials / Observational_studies / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2020 Document type: Article Country of publication: