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Validation of a sensitive UHPLC-MS/MS method for cytochrome P450 probe substrates caffeine, tolbutamide, dextromethorphan, and alprazolam in human serum reveals drug contamination of serum used for research.
Chen, Luying; van Breemen, Richard B.
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  • Chen L; Linus Pauling Institute and Department of Pharmaceutical Sciences, Oregon State University, 2900 SW Campus Way, Corvallis, OR, 97331 USA; UIC/NIH Center for Botanical Dietary Supplements Research, University of Illinois at Chicago, 833 S. Wood St., Chicago, IL 60612 USA.
  • van Breemen RB; Linus Pauling Institute and Department of Pharmaceutical Sciences, Oregon State University, 2900 SW Campus Way, Corvallis, OR, 97331 USA; UIC/NIH Center for Botanical Dietary Supplements Research, University of Illinois at Chicago, 833 S. Wood St., Chicago, IL 60612 USA. Electronic address: richard.vanbreemen@oregonstate.edu.
J Pharm Biomed Anal ; 179: 112983, 2020 Feb 05.
Article in En | MEDLINE | ID: mdl-31744669
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tolbutamide / Alprazolam / Caffeine / Chromatography, High Pressure Liquid / Serum / Dextromethorphan / Tandem Mass Spectrometry Type of study: Diagnostic_studies / Guideline Limits: Humans Language: En Journal: J Pharm Biomed Anal Year: 2020 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tolbutamide / Alprazolam / Caffeine / Chromatography, High Pressure Liquid / Serum / Dextromethorphan / Tandem Mass Spectrometry Type of study: Diagnostic_studies / Guideline Limits: Humans Language: En Journal: J Pharm Biomed Anal Year: 2020 Document type: Article Country of publication: