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Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants.
Satterstrom, F Kyle; Walters, Raymond K; Singh, Tarjinder; Wigdor, Emilie M; Lescai, Francesco; Demontis, Ditte; Kosmicki, Jack A; Grove, Jakob; Stevens, Christine; Bybjerg-Grauholm, Jonas; Bækvad-Hansen, Marie; Palmer, Duncan S; Maller, Julian B; Nordentoft, Merete; Mors, Ole; Robinson, Elise B; Hougaard, David M; Werge, Thomas M; Bo Mortensen, Preben; Neale, Benjamin M; Børglum, Anders D; Daly, Mark J.
Affiliation
  • Satterstrom FK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. satterst@broadinstitute.org.
  • Walters RK; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. satterst@broadinstitute.org.
  • Singh T; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. satterst@broadinstitute.org.
  • Wigdor EM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Lescai F; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Demontis D; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Kosmicki JA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Grove J; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Stevens C; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Bybjerg-Grauholm J; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Bækvad-Hansen M; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Palmer DS; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Maller JB; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.
  • Nordentoft M; Department of Biomedicine-Human Genetics, Aarhus University, Aarhus, Denmark.
  • Mors O; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.
  • Robinson EB; iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark.
  • Hougaard DM; Department of Biomedicine-Human Genetics, Aarhus University, Aarhus, Denmark.
  • Werge TM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Bo Mortensen P; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Neale BM; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Børglum AD; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.
  • Daly MJ; iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark.
Nat Neurosci ; 22(12): 1961-1965, 2019 12.
Article in En | MEDLINE | ID: mdl-31768057
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Attention Deficit Disorder with Hyperactivity / Genetic Variation / Genetic Predisposition to Disease / Autism Spectrum Disorder / Microtubule-Associated Proteins Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Nat Neurosci Journal subject: NEUROLOGIA Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Attention Deficit Disorder with Hyperactivity / Genetic Variation / Genetic Predisposition to Disease / Autism Spectrum Disorder / Microtubule-Associated Proteins Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Nat Neurosci Journal subject: NEUROLOGIA Year: 2019 Document type: Article Affiliation country: Country of publication: