Designing Highly Luminescent Cellulose Nanocrystals with Modulated Morphology for Multifunctional Bioimaging Materials.
ACS Appl Mater Interfaces
; 11(51): 48192-48201, 2019 Dec 26.
Article
in En
| MEDLINE
| ID: mdl-31789013
ABSTRACT
Spherical cellulose nanocrystals (SCNs) and rod-shaped cellulose nanocrystals (RCNs) were extracted from different cellulose materials. The two shape forms of cellulose nanocrystals (CNs) were designed with a combination of isothiocyanate (FITC), and both the obtained FITC-SCNs and FITC-RCNs exhibited high fluorescence brightness. The surfaces of SCNs and RCNs were subjected to a secondary imino group by a Schiff reaction and then covalently bonded to the isothiocyanate group of FITC through a secondary imino group to obtain fluorescent cellulose nanocrystals (FITC-CNs). The absolute ζ-potential and dispersion stability of FITC-CNs (FITC-SCNs and FITC-RCNs) were improved, which also promoted the increase in the fluorescence quantum yield. FITC-RCNs had a fluorescence quantum yield of 30.7%, and FITC-SCNs had a morphological advantage (better dispersion, etc.), resulting in a higher fluorescence quantum yield of 35.9%. Cell cytotoxicity experiments demonstrated that the process of FITC-CNs entering mouse osteoblasts (MC3T3) did not destroy the cell membrane, showing good biocompatibility. On the other hand, FITC-CNs with good dispersibility can significantly enhance poly(vinyl alcohol) (PVA) and poly(lactic acid) (PLA); their mechanical properties were improved (the highest sample reached to 243%) and their fluorescent properties were imparted. This study provides a simple surface functionalization method to produce high-luminance fluorescent materials for bioimaging, multifunctional nanoenhancement/dispersion marking, and anticounterfeiting materials.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cellulose
/
Nanocomposites
/
Nanoparticles
Language:
En
Journal:
ACS Appl Mater Interfaces
Journal subject:
BIOTECNOLOGIA
/
ENGENHARIA BIOMEDICA
Year:
2019
Document type:
Article
Affiliation country: