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Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC.
Kargl, Julia; Zhu, Xiaodong; Zhang, Huajia; Yang, Grace H Y; Friesen, Travis J; Shipley, Melissa; Maeda, Dean Y; Zebala, John A; McKay-Fleisch, Jill; Meredith, Gavin; Mashadi-Hossein, Afshin; Baik, Christina; Pierce, Robert H; Redman, Mary W; Thompson, Jeffrey C; Albelda, Steven M; Bolouri, Hamid; Houghton, A McGarry.
Affiliation
  • Kargl J; Fred Hutchinson Clinical Research Division, Seattle, Washington, USA.
  • Zhu X; Otto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria.
  • Zhang H; Fred Hutchinson Clinical Research Division, Seattle, Washington, USA.
  • Yang GHY; Fred Hutchinson Clinical Research Division, Seattle, Washington, USA.
  • Friesen TJ; Fred Hutchinson Clinical Research Division, Seattle, Washington, USA.
  • Shipley M; Fred Hutchinson Clinical Research Division, Seattle, Washington, USA.
  • Maeda DY; Fred Hutchinson Clinical Research Division, Seattle, Washington, USA.
  • Zebala JA; Syntrix Pharmaceuticals, Auburn, Washington, USA.
  • McKay-Fleisch J; Syntrix Pharmaceuticals, Auburn, Washington, USA.
  • Meredith G; Nanostring Inc., Seattle, Washington, USA.
  • Mashadi-Hossein A; Nanostring Inc., Seattle, Washington, USA.
  • Baik C; Nanostring Inc., Seattle, Washington, USA.
  • Pierce RH; Fred Hutchinson Clinical Research Division, Seattle, Washington, USA.
  • Redman MW; Fred Hutchinson Clinical Research Division, Seattle, Washington, USA.
  • Thompson JC; Fred Hutchinson Clinical Research Division, Seattle, Washington, USA.
  • Albelda SM; Division of Pulmonary, Allergy, and Critical Care Medicine, Thoracic Oncology Group, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
  • Bolouri H; Division of Pulmonary, Allergy, and Critical Care Medicine, Thoracic Oncology Group, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
  • Houghton AM; Human Biology Division, Fred Hutchinson Cancer Research Division, Seattle, Washington, USA.
JCI Insight ; 4(24)2019 12 19.
Article in En | MEDLINE | ID: mdl-31852845
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocytes, Tumor-Infiltrating / Carcinoma, Non-Small-Cell Lung / Antineoplastic Agents, Immunological / Lung Neoplasms / Neutrophils Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: JCI Insight Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocytes, Tumor-Infiltrating / Carcinoma, Non-Small-Cell Lung / Antineoplastic Agents, Immunological / Lung Neoplasms / Neutrophils Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: JCI Insight Year: 2019 Document type: Article Affiliation country: Country of publication: