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A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans.
Pendergrass, Sarah A; Buyske, Steven; Jeff, Janina M; Frase, Alex; Dudek, Scott; Bradford, Yuki; Ambite, Jose-Luis; Avery, Christy L; Buzkova, Petra; Deelman, Ewa; Fesinmeyer, Megan D; Haiman, Christopher; Heiss, Gerardo; Hindorff, Lucia A; Hsu, Chun-Nan; Jackson, Rebecca D; Lin, Yi; Le Marchand, Loic; Matise, Tara C; Monroe, Kristine R; Moreland, Larry; North, Kari E; Park, Sungshim L; Reiner, Alex; Wallace, Robert; Wilkens, Lynne R; Kooperberg, Charles; Ritchie, Marylyn D; Crawford, Dana C.
Affiliation
  • Pendergrass SA; Genentech, Inc., South San Francisco, California, United States of America.
  • Buyske S; Department of Statistics, Rutgers University, Piscataway, New Jersey, United States of America.
  • Jeff JM; Department of Genetics, Rutgers University, Piscataway, New Jersey, United States of America.
  • Frase A; Illumina, Inc., San Diego, California, United States of America.
  • Dudek S; Department of Genetics, Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Bradford Y; Department of Genetics, Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Ambite JL; Department of Genetics, Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Avery CL; Information Sciences Institute; University of Southern California, Marina del Rey, California, United States of America.
  • Buzkova P; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, United States of America.
  • Deelman E; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
  • Fesinmeyer MD; Information Sciences Institute; University of Southern California, Marina del Rey, California, United States of America.
  • Haiman C; Amgen, Thousand Oaks, California, United States of America.
  • Heiss G; Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, United States of America.
  • Hindorff LA; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, United States of America.
  • Hsu CN; Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, North Carolina, United States of America.
  • Jackson RD; National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Lin Y; Center for Research in Biological Systems, Department of Neurosciences, University of California, San Diego, La Jolla, California, United States of America.
  • Le Marchand L; The Ohio State University, Columbus, Ohio, United States of America.
  • Matise TC; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
  • Monroe KR; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, United States of America.
  • Moreland L; Department of Genetics, Rutgers University, Piscataway, New Jersey, United States of America.
  • North KE; Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, United States of America.
  • Park SL; University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Reiner A; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, United States of America.
  • Wallace R; Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, North Carolina, United States of America.
  • Wilkens LR; Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, United States of America.
  • Kooperberg C; Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.
  • Ritchie MD; Departments of Epidemiology and Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America.
  • Crawford DC; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, United States of America.
PLoS One ; 14(12): e0226771, 2019.
Article in En | MEDLINE | ID: mdl-31891604
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Black or African American / Atherosclerosis / Metagenomics / Genetic Pleiotropy / Phenomics Type of study: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Black or African American / Atherosclerosis / Metagenomics / Genetic Pleiotropy / Phenomics Type of study: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article Affiliation country: Country of publication: