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Protein kinase C-delta inhibition is organ-protective, enhances pathogen clearance, and improves survival in sepsis.
Liverani, Elisabetta; Tursi, Sarah A; Cornwell, William D; Mondrinos, Mark J; Sun, Shuang; Buttaro, Bettina A; Wolfson, Marla R; Rogers, Thomas J; Tükel, Çagla; Kilpatrick, Laurie E.
Affiliation
  • Liverani E; Center for Inflammation, Clinical and Translational Lung Research, Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
  • Tursi SA; Thrombosis Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
  • Cornwell WD; Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
  • Mondrinos MJ; Center for Inflammation, Clinical and Translational Lung Research, Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
  • Sun S; Center for Inflammation, Clinical and Translational Lung Research, Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
  • Buttaro BA; Thrombosis Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
  • Wolfson MR; Center for Inflammation, Clinical and Translational Lung Research, Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
  • Rogers TJ; Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
  • Tükel Ç; Center for Inflammation, Clinical and Translational Lung Research, Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
  • Kilpatrick LE; Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
FASEB J ; 34(2): 2497-2510, 2020 02.
Article in En | MEDLINE | ID: mdl-31908004
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / Macrophages, Peritoneal / Sepsis / Enzyme Inhibitors / Protein Kinase C-delta / Neutrophils Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2020 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / Macrophages, Peritoneal / Sepsis / Enzyme Inhibitors / Protein Kinase C-delta / Neutrophils Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2020 Document type: Article Affiliation country: Country of publication: