A case of myelodysplastic syndrome with t(10;18)(q26;q21).
J Lab Physicians
; 11(4): 382-384, 2019.
Article
in En
| MEDLINE
| ID: mdl-31929708
An 82-year-old male was admitted. Pancytopenia, a slightly low white blood cell count (3400/µL), and low levels of red blood cells (2.65 × 106/µL), hemoglobin (10.4 g/dL), and platelets (118,000/µL) were observed. Bone marrow aspiration was performed, revealing hypocellular bone marrow and normal blast levels (0.6%) with no dysplasia. G-banding chromosome analysis revealed the karyotype 45,X,-Y[3]/45, idem, t(10;18)(q26;q21)[13]/46,XY[4]. The patient was diagnosed with myelodysplastic syndrome, unclassified (MDS-U). This is the first case report demonstrating a patient with the chromosomal translocation, t(14;18)(q32;q21), which is extremely rare. This chromosomal aberration was critical for the diagnosis of MDS in this patient.
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01-internacional
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MEDLINE
Language:
En
Journal:
J Lab Physicians
Year:
2019
Document type:
Article
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