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Thermal shift assay: Strengths and weaknesses of the method to investigate the ligand-induced thermostabilization of soluble guanylyl cyclase.
Elgert, Christin; Rühle, Anne; Sandner, Peter; Behrends, Sönke.
Affiliation
  • Elgert C; Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Braunschweig - Institute of Technology, Germany. Electronic address: c.elgert@tu-braunschweig.de.
  • Rühle A; Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Braunschweig - Institute of Technology, Germany. Electronic address: a.ruehle@tu-braunschweig.de.
  • Sandner P; Bayer AG, Drug Discovery, Wuppertal, Germany. Electronic address: peter.sandner@bayer.com.
  • Behrends S; Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Braunschweig - Institute of Technology, Germany. Electronic address: s.behrends@tu-braunschweig.de.
J Pharm Biomed Anal ; 181: 113065, 2020 Mar 20.
Article in En | MEDLINE | ID: mdl-32032919
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enzyme Stability / Differential Thermal Analysis / Soluble Guanylyl Cyclase Language: En Journal: J Pharm Biomed Anal Year: 2020 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enzyme Stability / Differential Thermal Analysis / Soluble Guanylyl Cyclase Language: En Journal: J Pharm Biomed Anal Year: 2020 Document type: Article Country of publication: