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IDOL regulates systemic energy balance through control of neuronal VLDLR expression.
Lee, Stephen D; Priest, Christina; Bjursell, Mikael; Gao, Jie; Arneson, Douglas V; Ahn, In Sook; Diamante, Graciel; van Veen, J Edward; Massa, Megan G; Calkin, Anna C; Kim, Jason; Andersén, Harriet; Rajbhandari, Prashant; Porritt, Michelle; Carreras, Alba; Ahnmark, Andrea; Seeliger, Frank; Maxvall, Ingela; Eliasson, Pernilla; Althage, Magnus; Åkerblad, Peter; Lindén, Daniel; Cole, Tracy A; Lee, Richard; Boyd, Helen; Bohlooly-Y, Mohammad; Correa, Stephanie M; Yang, Xia; Tontonoz, Peter; Hong, Cynthia.
Affiliation
  • Lee SD; Department of Pathology and Laboratory Medicine, Department of Biological Chemistry, and Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • Priest C; Department of Pathology and Laboratory Medicine, Department of Biological Chemistry, and Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • Bjursell M; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Gao J; Department of Pathology and Laboratory Medicine, Department of Biological Chemistry, and Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • Arneson DV; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Ahn IS; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Diamante G; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • van Veen JE; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Massa MG; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Calkin AC; Department of Pathology and Laboratory Medicine, Department of Biological Chemistry, and Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • Kim J; Department of Pathology and Laboratory Medicine, Department of Biological Chemistry, and Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • Andersén H; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Rajbhandari P; Department of Pathology and Laboratory Medicine, Department of Biological Chemistry, and Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • Porritt M; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Carreras A; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Ahnmark A; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Seeliger F; Pathology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Maxvall I; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Eliasson P; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Althage M; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Åkerblad P; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Lindén D; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Cole TA; Division of Endocrinology, Department of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Lee R; Central Nervous System Group, Antisense Drug Discovery, Ionis Pharmaceuticals, Inc, Carlsbad, CA, USA.
  • Boyd H; Central Nervous System Group, Antisense Drug Discovery, Ionis Pharmaceuticals, Inc, Carlsbad, CA, USA.
  • Bohlooly-Y M; Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca; Cambridge Science Park, Cambridge, UK.
  • Correa SM; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Yang X; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Tontonoz P; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Hong C; Department of Pathology and Laboratory Medicine, Department of Biological Chemistry, and Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. PTontonoz@mednet.ucla.edu.
Nat Metab ; 1(11): 1089-1100, 2019 11.
Article in En | MEDLINE | ID: mdl-32072135

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, LDL / Ubiquitin-Protein Ligases / Energy Metabolism / Neurons Limits: Animals Language: En Journal: Nat Metab Year: 2019 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, LDL / Ubiquitin-Protein Ligases / Energy Metabolism / Neurons Limits: Animals Language: En Journal: Nat Metab Year: 2019 Document type: Article Affiliation country: