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Identification and preclinical development of an anti-proteolytic uPA antibody for rheumatoid arthritis.
Almholt, Kasper; Wang, Jishu; Pass, Jesper; Røder, Gustav; Padkjær, Søren B; Hebsgaard, Josephine B; Xia, Wenjuan; Yang, Li; Forsell, Johan; Breinholt, Vibeke M; Thygesen, Peter; Agersø, Henrik; Loftager, Mette; Usher, Pernille A.
Affiliation
  • Almholt K; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark. KAHL@novonordisk.com.
  • Wang J; Global Research Technologies, Novo Nordisk China R&D, Beijing, China.
  • Pass J; Global Research Technologies, Novo Nordisk A/S, Måløv, Denmark.
  • Røder G; Global Research Technologies, Novo Nordisk A/S, Måløv, Denmark.
  • Padkjær SB; Global Research Technologies, Novo Nordisk A/S, Måløv, Denmark.
  • Hebsgaard JB; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Xia W; Global Research Technologies, Novo Nordisk China R&D, Beijing, China.
  • Yang L; Global Research Technologies, Novo Nordisk China R&D, Beijing, China.
  • Forsell J; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Breinholt VM; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Thygesen P; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Agersø H; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Loftager M; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Usher PA; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
J Mol Med (Berl) ; 98(4): 585-593, 2020 04.
Article in En | MEDLINE | ID: mdl-32108909
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Urokinase-Type Plasminogen Activator / Antirheumatic Agents / Drug Development / Antibodies, Monoclonal Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: J Mol Med (Berl) Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Urokinase-Type Plasminogen Activator / Antirheumatic Agents / Drug Development / Antibodies, Monoclonal Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: J Mol Med (Berl) Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2020 Document type: Article Affiliation country: Country of publication: