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Gefapixant, a P2X3 receptor antagonist, for the treatment of refractory or unexplained chronic cough: a randomised, double-blind, controlled, parallel-group, phase 2b trial.
Smith, Jaclyn A; Kitt, Michael M; Morice, Alyn H; Birring, Surinder S; McGarvey, Lorcan P; Sher, Mandel R; Li, Yu-Ping; Wu, Wen-Chi; Xu, Zhi Jin; Muccino, David R; Ford, Anthony P.
Affiliation
  • Smith JA; Division of Infection, Immunity, and Respiratory Medicine, University of Manchester, Manchester, UK; Manchester University NHS Foundation Trust, Manchester, UK. Electronic address: jacky.smith@manchester.ac.uk.
  • Kitt MM; Merck & Co., Kenilworth, NJ, USA.
  • Morice AH; Hull York Medical School, Cottingham, UK.
  • Birring SS; Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.
  • McGarvey LP; Centre for Experimental Medicine, Queen's University Belfast, Belfast, UK.
  • Sher MR; Center for Cough, Largo, FL, USA.
  • Li YP; GetStat Solutions, LLC, Palo Alto, CA, USA.
  • Wu WC; Merck & Co., Kenilworth, NJ, USA.
  • Xu ZJ; Merck & Co., Kenilworth, NJ, USA.
  • Muccino DR; Merck & Co., Kenilworth, NJ, USA.
  • Ford AP; Merck & Co., Kenilworth, NJ, USA.
Lancet Respir Med ; 8(8): 775-785, 2020 08.
Article in En | MEDLINE | ID: mdl-32109425
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Sulfonamides / Chronic Disease / Cough / Purinergic P2X Receptor Antagonists Type of study: Clinical_trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: America do norte / Europa Language: En Journal: Lancet Respir Med Year: 2020 Document type: Article Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Sulfonamides / Chronic Disease / Cough / Purinergic P2X Receptor Antagonists Type of study: Clinical_trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: America do norte / Europa Language: En Journal: Lancet Respir Med Year: 2020 Document type: Article Country of publication: