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Single-Pass vs 2-Pass Endoscopic Ultrasound-Guided Fine-Needle Biopsy Sample Collection for Creation of Pancreatic Adenocarcinoma Organoids.
Lacomb, Joseph F; Plenker, Dennis; Tiriac, Hervé; Bucobo, Juan Carlos; D'souza, Lionel S; Khokhar, Asim S; Patel, Hardik; Channer, Breana; Joseph, Dimitri; Wu, Maoxin; Tuveson, David A; Li, Ellen; Buscaglia, Jonathan M.
Affiliation
  • Lacomb JF; Division of Gastroenterology and Hepatology, Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York, USA.
  • Plenker D; Cold Spring Harbor Laboratory, Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.
  • Tiriac H; Cold Spring Harbor Laboratory, Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.
  • Bucobo JC; Division of Gastroenterology and Hepatology, Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York, USA.
  • D'souza LS; Division of Gastroenterology and Hepatology, Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York, USA.
  • Khokhar AS; Division of Gastroenterology and Hepatology, Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York, USA.
  • Patel H; Cold Spring Harbor Laboratory, Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.
  • Channer B; Division of Gastroenterology and Hepatology, Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York, USA.
  • Joseph D; Division of Gastroenterology and Hepatology, Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York, USA.
  • Wu M; Division of Cytopathology, Department of Pathology, Stony Brook University School of Medicine, Stony Brook, New York, USA.
  • Tuveson DA; Cold Spring Harbor Laboratory, Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.
  • Li E; Division of Gastroenterology and Hepatology, Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York, USA.
  • Buscaglia JM; Division of Gastroenterology and Hepatology, Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York, USA. Electronic address: jonathan.buscaglia@stonybrookmedicine.edu.
Clin Gastroenterol Hepatol ; 19(4): 845-847, 2021 04.
Article in En | MEDLINE | ID: mdl-32119924
ABSTRACT
Pancreatic ductal adenocarcinoma (PDAC) has one of the poorest prognoses of all malignancies, with a 5-year survival rate <8%.1,2 Suspicious lesions are typically diagnosed via endoscopic ultrasound-guided fine-needle aspiration or endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB).3 Fewer needle passes decreases the risk of postprocedure complications, including pancreatitis and hemorrhage, while allowing additional needle passes to be used for adjuvant tissue testing, such as organoid creation and DNA sequencing.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Adenocarcinoma / Endoscopic Ultrasound-Guided Fine Needle Aspiration Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Clin Gastroenterol Hepatol Journal subject: GASTROENTEROLOGIA Year: 2021 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Adenocarcinoma / Endoscopic Ultrasound-Guided Fine Needle Aspiration Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Clin Gastroenterol Hepatol Journal subject: GASTROENTEROLOGIA Year: 2021 Document type: Article Affiliation country: