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Binding to heparin triggers deleterious structural and biochemical changes in human low-density lipoprotein, which are amplified in hyperglycemia.
Jayaraman, Shobini; Chavez, Olivia R; Pérez, Antonio; Miñambres, Inka; Sánchez-Quesada, Jose Luis; Gursky, Olga.
Affiliation
  • Jayaraman S; Department of Physiology & Biophysics, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address: shobini@bu.edu.
  • Chavez OR; Department of Physiology & Biophysics, Boston University School of Medicine, Boston, MA 02118, USA.
  • Pérez A; Endocrinology Department of the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; CIBER of Diabetes and Metabolic Diseases (CIBERDEM), Spain.
  • Miñambres I; Endocrinology Department of the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
  • Sánchez-Quesada JL; CIBER of Diabetes and Metabolic Diseases (CIBERDEM), Spain; Cardiovascular Biochemistry Group, Research Institute of the Hospital de Sant Pau, CIBERDEM, Barcelona, Spain.
  • Gursky O; Department of Physiology & Biophysics, Boston University School of Medicine, Boston, MA 02118, USA; Amyloidosis Treatment and Research Center, Boston University School of Medicine, Boston MA, USA.
Biochim Biophys Acta Mol Cell Biol Lipids ; 1865(8): 158712, 2020 08.
Article in En | MEDLINE | ID: mdl-32289504
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heparin / Diabetes Mellitus, Type 2 / Hyperglycemia / Lipoproteins, LDL Limits: Humans Language: En Journal: Biochim Biophys Acta Mol Cell Biol Lipids Year: 2020 Document type: Article
Fulltext
Add to My VHL
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heparin / Diabetes Mellitus, Type 2 / Hyperglycemia / Lipoproteins, LDL Limits: Humans Language: En Journal: Biochim Biophys Acta Mol Cell Biol Lipids Year: 2020 Document type: Article