[A survey on clinical characteristics and risk factors of severe asthma in China].
Zhonghua Yi Xue Za Zhi
; 100(14): 1106-1111, 2020 Apr 14.
Article
in Zh
| MEDLINE
| ID: mdl-32294877
ABSTRACT
Objective:
To investigate the clinical characteristics and risk factors of severe bronchial asthma in Chinese people over 14 years old.Methods:
According to the multi-stage random cluster sampling methods, a total of 164 215 subjects were visited by a questionnaire in the epidemiology survey from eight provinces (Beijing, Shanghai, Guangdong, Liaoning, Henan, Shanxi, Jiangsu, Sichuan provinces) located in seven regions (north, northeast, east, central China, south, southwest and northwest) of China from February 2010 to August 2012. A total of 2 034 were diagnosed as asthma. The clinical characteristics and related risk factors of patients with severe asthma in China were analyzed.Results:
Among all asthma patients, 560 were newly diagnosed, accounting for 27.5% (560/2 034) and the percentage of previously confirmed patients was 72.5% (1 474/2 034). A total of 145 were eligible for severe asthma, accounting for 9.8% (145/1 474) of previously confirmed asthmatics and 7.1% (145/2 034) of all asthmatics. 83.5% (121/145) severe asthmatics had at least one trigger factor. Correlation analysis showed that the risk factors of severe asthma were smoking (OR=1.543, 95%CI 1.250-1.814), obesity (OR=2.186, 95%CI 1.972-2.354), petting (OR=2.135, 95%CI 1.904-2.283), combined with allergic rhinitis (OR=3.456, 95%CI 2.721-4.326), gastroesophageal reflux disease (OR=1.842, 95%CI 1.682-2.140), bronchiectasis (OR=1.665, 95%CI 1.347-1.912) or chronic obstructive pulmonary disease (OR=1.312, 95%CI 1.171-1.694).Conclusions:
The most common comorbidities in severe asthmatics in China are allergic rhinitis and gastroesophageal reflux disease. The risk factors of severe asthma include obesity, allergic rhinitis, gastroesophageal reflux disease, chronic obstructive pulmonary disease, bronchiectasis, smoking and petting.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Asthma
Type of study:
Etiology_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Humans
Country/Region as subject:
Asia
Language:
Zh
Journal:
Zhonghua Yi Xue Za Zhi
Year:
2020
Document type:
Article
Affiliation country: