Potential pathophysiological mechanisms leading to increased COVID-19 susceptibility and severity in obesity.
Obes Med
; 19: 100259, 2020 Sep.
Article
in En
| MEDLINE
| ID: mdl-32501427
ABSTRACT
As we are facing worldwide pandemic of COVID-19, we aimed to identify potential pathophysiological mechanisms leading to increased COVID-19 susceptibility and severity in obesity. Special emphasis will be given on increased susceptibility to infections due to obesity-related low-grade chronic inflammation, higher expression of angiotensin converting enzyme-2 and pathway-associated components, as well as decreased vitamin D bioavailability, since all of them provide easier ways for the virus to enter into host cells, replicate and stunt adequate immune responses.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Obes Med
Year:
2020
Document type:
Article
Affiliation country: