Intracellular location matters: rationalization of the anti-inflammatory activity of a manganese(ii) superoxide dismutase mimic complex.
Chem Commun (Camb)
; 56(57): 7885-7888, 2020 Jul 21.
Article
in En
| MEDLINE
| ID: mdl-32520039
ABSTRACT
A conjugate of a Mn-based superoxide dismutase mimic with a Re-based multimodal probe 1[combining low line] was studied in a cellular model of oxidative stress. Its speciation was investigated using Re and Mn X-fluorescence. Interestingly, 1[combining low line] shows a distribution different from its unconjugated analogue but a similar concentration in mitochondria and a similar bioactivity.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rhenium
/
Superoxide Dismutase
/
Anti-Inflammatory Agents, Non-Steroidal
/
Coordination Complexes
Limits:
Humans
Language:
En
Journal:
Chem Commun (Camb)
Journal subject:
QUIMICA
Year:
2020
Document type:
Article
Affiliation country: