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An unbiased high-throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer.
Pan, Chun-Hao; Otsuka, Yuka; Sridharan, BanuPriya; Woo, Melissa; Leiton, Cindy V; Babu, Sruthi; Torrente Gonçalves, Mariana; Kawalerski, Ryan R; K Bai, Ji Dong; Chang, David K; Biankin, Andrew V; Scampavia, Louis; Spicer, Timothy; Escobar-Hoyos, Luisa F; Shroyer, Kenneth R.
Affiliation
  • Pan CH; Department of Pathology, Renaissance School of Medicine, Stony Brook University, NY, USA.
  • Otsuka Y; Molecular and Cellular Biology Graduate Program, Stony Brook University, NY, USA.
  • Sridharan B; The Scripps Research Institute, Jupiter, FL, USA.
  • Woo M; In vitro In vivo Translation, GSK, Collegeville, PA, USA.
  • Leiton CV; Department of Pathology, Renaissance School of Medicine, Stony Brook University, NY, USA.
  • Babu S; Simons Summer Research Program, Stony Brook University, NY, USA.
  • Torrente Gonçalves M; Department of Pathology, Renaissance School of Medicine, Stony Brook University, NY, USA.
  • Kawalerski RR; Department of Pathology, Renaissance School of Medicine, Stony Brook University, NY, USA.
  • K Bai JD; Department of Family, Population & Preventive Medicine, Renaissance School of Medicine, Stony Brook University, NY, USA.
  • Chang DK; Department of Pathology, Renaissance School of Medicine, Stony Brook University, NY, USA.
  • Biankin AV; Department of Pathology, Renaissance School of Medicine, Stony Brook University, NY, USA.
  • Scampavia L; Department of Pathology, Renaissance School of Medicine, Stony Brook University, NY, USA.
  • Spicer T; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, UK.
  • Escobar-Hoyos LF; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, UK.
  • Shroyer KR; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, UK.
Mol Oncol ; 14(8): 1800-1816, 2020 08.
Article in En | MEDLINE | ID: mdl-32533886
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Drug Screening Assays, Antitumor / High-Throughput Screening Assays Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Oncol Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Drug Screening Assays, Antitumor / High-Throughput Screening Assays Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Oncol Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2020 Document type: Article Affiliation country: Country of publication: