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Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2α-dependent mechanism.
Riopel, Matthew; Moon, Jae-Su; Bandyopadhyay, Gautam K; You, Seohee; Lam, Kevin; Liu, Xiao; Kisseleva, Tatiana; Brenner, David; Lee, Yun Sok.
Affiliation
  • Riopel M; Division of Endocrinology & Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Moon JS; Division of Endocrinology & Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Bandyopadhyay GK; Division of Endocrinology & Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
  • You S; Cardiovascular and Metabolism, Janssen Research & Development, Spring House, PA, USA.
  • Lam K; Department of Surgery, University of California, San Diego, La Jolla, CA, USA.
  • Liu X; Department of Surgery, University of California, San Diego, La Jolla, CA, USA.
  • Kisseleva T; Department of Surgery, University of California, San Diego, La Jolla, CA, USA.
  • Brenner D; Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Lee YS; Division of Endocrinology & Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA, USA. Electronic address: yunsoklee@ucsd.edu.
Mol Metab ; 41: 101039, 2020 11.
Article in En | MEDLINE | ID: mdl-32534258
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Basic Helix-Loop-Helix Transcription Factors / Prolyl-Hydroxylase Inhibitors / Insulin Type of study: Diagnostic_studies Limits: Animals / Humans / Male Language: En Journal: Mol Metab Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Basic Helix-Loop-Helix Transcription Factors / Prolyl-Hydroxylase Inhibitors / Insulin Type of study: Diagnostic_studies Limits: Animals / Humans / Male Language: En Journal: Mol Metab Year: 2020 Document type: Article Affiliation country: Country of publication: