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Resection and repair of a Cas9 double-strand break at CTG trinucleotide repeats induces local and extensive chromosomal deletions.
Mosbach, Valentine; Viterbo, David; Descorps-Declère, Stéphane; Poggi, Lucie; Vaysse-Zinkhöfer, Wilhelm; Richard, Guy-Franck.
Affiliation
  • Mosbach V; Institut Pasteur, CNRS, UMR3525, Paris, France.
  • Viterbo D; Institut Pasteur, CNRS, UMR3525, Paris, France.
  • Descorps-Declère S; Institut Pasteur, CNRS, UMR3525, Paris, France.
  • Poggi L; Institut Pasteur, Center of Bioinformatics, Biostatistics and Integrative Biology (C3BI), Paris, France.
  • Vaysse-Zinkhöfer W; Institut Pasteur, CNRS, UMR3525, Paris, France.
  • Richard GF; Sorbonne Universités, Collège doctoral, Paris, France.
PLoS Genet ; 16(7): e1008924, 2020 07.
Article in En | MEDLINE | ID: mdl-32673314
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombination, Genetic / Trinucleotide Repeats / DNA Breaks, Double-Stranded / Myotonic Dystrophy Limits: Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2020 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombination, Genetic / Trinucleotide Repeats / DNA Breaks, Double-Stranded / Myotonic Dystrophy Limits: Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2020 Document type: Article Affiliation country: