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Angiotensin-(1-9) prevents vascular remodeling by decreasing vascular smooth muscle cell dedifferentiation through a FoxO1-dependent mechanism.
Norambuena-Soto, Ignacio; Ocaranza, Maria Paz; Cancino-Arenas, Nicole; Sanhueza-Olivares, Fernanda; Villar-Fincheira, Paulina; Leiva-Navarrete, Sebastian; Mancilla-Medina, Cristian; Moya, Jacqueline; Novoa, Ulises; Jalil, Jorge E; Castro, Pablo F; Lavandero, Sergio; Chiong, Mario.
Affiliation
  • Norambuena-Soto I; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.
  • Ocaranza MP; Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Center of New Drugs for Hypertension (CENDHY), Universidad de Chile & Pontificia Universidad Católica de Chile, Santiago, Chile; Advanced Center for Ch
  • Cancino-Arenas N; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.
  • Sanhueza-Olivares F; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.
  • Villar-Fincheira P; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.
  • Leiva-Navarrete S; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.
  • Mancilla-Medina C; Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Center of New Drugs for Hypertension (CENDHY), Universidad de Chile & Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Moya J; Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Center of New Drugs for Hypertension (CENDHY), Universidad de Chile & Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Novoa U; Departamento de Ciencias Básicas Biomédicas, Facultad de Ciencias de la Salud, Universidad de Talca, Chile.
  • Jalil JE; Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Center of New Drugs for Hypertension (CENDHY), Universidad de Chile & Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Castro PF; Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Lavandero S; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile; Corporacion Centro de Estudios Científicos de las Enfermedades Crónicas (CECEC), Santiago, Chile; Department of Internal Medicine (Cardiolo
  • Chiong M; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile. Electronic address: mchiong@ciq.uchile.cl.
Biochem Pharmacol ; 180: 114190, 2020 10.
Article in En | MEDLINE | ID: mdl-32768401
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Angiotensin I / Cell Dedifferentiation / Vascular Remodeling / Muscle, Smooth, Vascular / Nerve Tissue Proteins / Antihypertensive Agents Limits: Animals Language: En Journal: Biochem Pharmacol Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Angiotensin I / Cell Dedifferentiation / Vascular Remodeling / Muscle, Smooth, Vascular / Nerve Tissue Proteins / Antihypertensive Agents Limits: Animals Language: En Journal: Biochem Pharmacol Year: 2020 Document type: Article Affiliation country: Country of publication: