Substantial Cellular Penetration of Fluorescent Imidazoquinoxalines.
J Fluoresc
; 30(6): 1499-1512, 2020 Dec.
Article
in En
| MEDLINE
| ID: mdl-32778995
ABSTRACT
Fluorescent tools have revolutionized our capability to visualize, probe, study, and understand the biological cellular properties, processes and dynamics, enabling researchers to improve their knowledge for example in cancer field. In this paper, we use the peculiar properties of our Imiqualines derivatives to study their cellular penetration and distribution in a human melanoma cell line A375 using confocal microscopy. Preliminary results on colocalization with the potent protein target c-Kit of our lead are also described.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Quinoxalines
/
Fluorescent Dyes
/
Imidazoles
Limits:
Humans
Language:
En
Journal:
J Fluoresc
Journal subject:
BIOFISICA
Year:
2020
Document type:
Article
Affiliation country: