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Comparison of MOG and AQP4 antibody seroprevalence in Korean adults with inflammatory demyelinating CNS diseases.
Hyun, Jae-Won; Lee, Hye Lim; Jeong, Woo Kyo; Lee, Hye Jung; Shin, Jong Hwa; Min, Ju-Hong; Kim, Byoung Joon; Kim, Seung Woo; Shin, Ha Young; Oh, Jeeyoung; Kim, Woojun; Shin, Hyun-June; Oh, Sun-Young; Kim, Hyunjin; Lim, Young-Min; Huh, So-Young; Cho, Eun Bin; Nam, Tai-Seung; Lee, Seung-Han; Kim, Sun-Young; Kang, Sa-Yoon; Han, Suk Geun; Sohn, Eun Hee; Baek, Seol-Hee; Kim, Byung-Jo; Lee, Sang-Soo; Seok, Jin Myoung; Hong, Yoon-Ho; Oh, Seong-Il; Kim, Jong Kuk; Shin, Kyong Jin; Kwon, Ohyun; Cho, Joong-Yang; Bae, Jong Seok; Kim, So Yeon; Kim, Yeseul; Lee, Min Young; Kim, Su-Hyun; Kim, Ho Jin.
Affiliation
  • Hyun JW; Department of Neurology, National Cancer Center, Goyang, Korea.
  • Lee HL; Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
  • Jeong WK; Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • Lee HJ; Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • Shin JH; Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • Min JH; Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • Kim BJ; Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • Kim SW; Yonsei University College of Medicine, Seoul, Korea.
  • Shin HY; Yonsei University College of Medicine, Seoul, Korea.
  • Oh J; School of Medicine, Konkuk University, Seoul, Korea.
  • Kim W; College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • Shin HJ; School of Medicine, Chonbuk National University, Jeonju, Korea.
  • Oh SY; School of Medicine, Chonbuk National University, Jeonju, Korea.
  • Kim H; Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  • Lim YM; Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  • Huh SY; College of Medicine, Kosin University, Busan, Korea.
  • Cho EB; Gyeongsang National University College of Medicine, Jinju, Korea.
  • Nam TS; Chonnam National University Medical School and Hospital, Gwangju, Korea.
  • Lee SH; Chonnam National University Medical School and Hospital, Gwangju, Korea.
  • Kim SY; Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
  • Kang SY; Jeju National University School of Medicine, Jeju, Korea.
  • Han SG; Samsung Changwon Medical Center, Sungkyunkwan University School of Medicine, Changwon, Korea.
  • Sohn EH; Chungnam National University Hospital, Daejeon, Korea.
  • Baek SH; Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.
  • Kim BJ; Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.
  • Lee SS; Chungbuk National University Hospital, Cheongju, Korea.
  • Seok JM; Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea.
  • Hong YH; Seoul National University College of Medicine, Neuroscience Research Institute, Seoul National University Medical Research Council, Seoul Metropolitan Government Boramae Medical Center, Seoul, Korea.
  • Oh SI; Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
  • Kim JK; Peripheral Neuropathy Research Center, Dong-A University, Busan, Korea.
  • Shin KJ; Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
  • Kwon O; Nowon Eulji Medical Center, Eulji University College of Medicine, Seoul, Korea.
  • Cho JY; Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
  • Bae JS; Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
  • Kim SY; Division of Clinical Research, National Cancer Center, Goyang, Korea.
  • Kim Y; Division of Clinical Research, National Cancer Center, Goyang, Korea.
  • Lee MY; Department of Neurology, National Cancer Center, Goyang, Korea.
  • Kim SH; Department of Neurology, National Cancer Center, Goyang, Korea.
  • Kim HJ; Department of Neurology, National Cancer Center, Goyang, Korea/Division of Clinical Research, National Cancer Center, Goyang, Korea.
Mult Scler ; 27(6): 964-967, 2021 05.
Article in En | MEDLINE | ID: mdl-32779521
ABSTRACT
We aimed to compare seroprevalence of anti-myelin oligodendrocyte glycoprotein (MOG) and anti-aquaporin-4 (AQP4) antibodies in Korean adults with inflammatory demyelinating diseases (IDDs) of the central nervous system (CNS), based on a multicenter nationwide database. Sera were analyzed using a live cell-based assay for MOG and AQP4 antibodies. Of 586 Korean adults with IDDs of the CNS, 36 (6.1%) and 185 (31.6%) tested positive for MOG and AQP4 antibodies, respectively. No participant showed double positivity. Seroprevalence of MOG antibodies was about five times lower than that of AQP4 antibodies in a large cohort of Korean adults with IDDs of the CNS.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Central Nervous System Diseases / Aquaporin 4 Type of study: Clinical_trials Limits: Adult / Humans Country/Region as subject: Asia Language: En Journal: Mult Scler Journal subject: NEUROLOGIA Year: 2021 Document type: Article
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Central Nervous System Diseases / Aquaporin 4 Type of study: Clinical_trials Limits: Adult / Humans Country/Region as subject: Asia Language: En Journal: Mult Scler Journal subject: NEUROLOGIA Year: 2021 Document type: Article