Comparison of MOG and AQP4 antibody seroprevalence in Korean adults with inflammatory demyelinating CNS diseases.
Mult Scler
; 27(6): 964-967, 2021 05.
Article
in En
| MEDLINE
| ID: mdl-32779521
ABSTRACT
We aimed to compare seroprevalence of anti-myelin oligodendrocyte glycoprotein (MOG) and anti-aquaporin-4 (AQP4) antibodies in Korean adults with inflammatory demyelinating diseases (IDDs) of the central nervous system (CNS), based on a multicenter nationwide database. Sera were analyzed using a live cell-based assay for MOG and AQP4 antibodies. Of 586 Korean adults with IDDs of the CNS, 36 (6.1%) and 185 (31.6%) tested positive for MOG and AQP4 antibodies, respectively. No participant showed double positivity. Seroprevalence of MOG antibodies was about five times lower than that of AQP4 antibodies in a large cohort of Korean adults with IDDs of the CNS.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Central Nervous System Diseases
/
Aquaporin 4
Type of study:
Clinical_trials
Limits:
Adult
/
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Mult Scler
Journal subject:
NEUROLOGIA
Year:
2021
Document type:
Article