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Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPß in Microglia.
Ndoja, Ada; Reja, Rohit; Lee, Seung-Hye; Webster, Joshua D; Ngu, Hai; Rose, Christopher M; Kirkpatrick, Donald S; Modrusan, Zora; Chen, Ying-Jiun Jasmine; Dugger, Debra L; Gandham, Vineela; Xie, Luke; Newton, Kim; Dixit, Vishva M.
Affiliation
  • Ndoja A; Department of Physiological Chemistry, Genentech, South San Francisco, CA 94080, USA.
  • Reja R; Department of Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, USA.
  • Lee SH; Department of Neuroscience, Genentech, South San Francisco, CA 94080, USA.
  • Webster JD; Department of Pathology, Genentech, South San Francisco, CA 94080, USA.
  • Ngu H; Department of Pathology, Genentech, South San Francisco, CA 94080, USA.
  • Rose CM; Department of Microchemistry, Proteomics, Lipidomics and Next Generation Sequencing, Genentech, South San Francisco, CA 94080, USA.
  • Kirkpatrick DS; Department of Microchemistry, Proteomics, Lipidomics and Next Generation Sequencing, Genentech, South San Francisco, CA 94080, USA.
  • Modrusan Z; Department of Microchemistry, Proteomics, Lipidomics and Next Generation Sequencing, Genentech, South San Francisco, CA 94080, USA.
  • Chen YJ; Department of Microchemistry, Proteomics, Lipidomics and Next Generation Sequencing, Genentech, South San Francisco, CA 94080, USA.
  • Dugger DL; Department of Physiological Chemistry, Genentech, South San Francisco, CA 94080, USA.
  • Gandham V; Department of Biomedical Imaging, Genentech, South San Francisco, CA 94080, USA.
  • Xie L; Department of Biomedical Imaging, Genentech, South San Francisco, CA 94080, USA.
  • Newton K; Department of Physiological Chemistry, Genentech, South San Francisco, CA 94080, USA. Electronic address: knewton@gene.com.
  • Dixit VM; Department of Physiological Chemistry, Genentech, South San Francisco, CA 94080, USA. Electronic address: dixit@gene.com.
Cell ; 182(5): 1156-1169.e12, 2020 09 03.
Article in En | MEDLINE | ID: mdl-32795415

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microglia / CCAAT-Enhancer-Binding Protein-beta / Ubiquitin / Ubiquitin-Protein Ligases / Ligases Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Cell Year: 2020 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microglia / CCAAT-Enhancer-Binding Protein-beta / Ubiquitin / Ubiquitin-Protein Ligases / Ligases Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Cell Year: 2020 Document type: Article Affiliation country: Country of publication: