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Sevoflurane depresses neurons in the medial parabrachial nucleus by potentiating postsynaptic GABAA receptors and background potassium channels.
Xu, Wei; Wang, Lu; Yuan, Xiang-Shan; Wang, Tian-Xiao; Li, Wen-Xian; Qu, Wei-Min; Hong, Zong-Yuan; Huang, Zhi-Li.
Affiliation
  • Xu W; Department of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Shanghai Medical College of Fudan University, Shanghai, China.
  • Wang L; Department of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Shanghai Medical College of Fudan University, Shanghai, China.
  • Yuan XS; Department of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Shanghai Medical College of Fudan University, Shanghai, China.
  • Wang TX; Department of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Shanghai Medical College of Fudan University, Shanghai, China.
  • Li WX; Department of Anesthesiology, The Eye, Ear, Nose and Throat Hospital of Fudan University, Shanghai Medical College of Fudan University, Shanghai, China.
  • Qu WM; Department of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Shanghai Medical College of Fudan University, Shanghai, China.
  • Hong ZY; Laboratory of Quantitative Pharmacology, Department of Pharmacology, Wannan Medical College, Wuhu, China.
  • Huang ZL; Department of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Shanghai Medical College of Fudan University, Shanghai, China. Electronic address: huangzl@fudan.edu.cn.
Neuropharmacology ; 181: 108249, 2020 12 15.
Article in En | MEDLINE | ID: mdl-32931816

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Potassium Channels / Receptors, GABA-A / Anesthetics, Inhalation / Parabrachial Nucleus / Sevoflurane / Neurons Limits: Animals Language: En Journal: Neuropharmacology Year: 2020 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Potassium Channels / Receptors, GABA-A / Anesthetics, Inhalation / Parabrachial Nucleus / Sevoflurane / Neurons Limits: Animals Language: En Journal: Neuropharmacology Year: 2020 Document type: Article Affiliation country: Country of publication: