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HZ-A-005, a potent, selective, and covalent Bruton's tyrosine kinase inhibitor in preclinical development.
Huang, Wenhai; Wang, Shu; Zhang, Zhimin; Zhang, Chixiao; Zeng, Shenxin; Liang, Meihao; Shen, Zhengrong; Liu, Xingguo.
Affiliation
  • Huang W; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Hangzhou Medical College, Hangzhou 310013, China.
  • Wang S; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Hangzhou Medical College, Hangzhou 310013, China.
  • Zhang Z; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Hangzhou Medical College, Hangzhou 310013, China.
  • Zhang C; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Hangzhou Medical College, Hangzhou 310013, China.
  • Zeng S; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Hangzhou Medical College, Hangzhou 310013, China.
  • Liang M; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Hangzhou Medical College, Hangzhou 310013, China.
  • Shen Z; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Hangzhou Medical College, Hangzhou 310013, China. Electronic address: Shenzr@zjams.com.cn.
  • Liu X; Hangzhou Hertz Pharmaceutical Co., Hangzhou 310018, China. Electronic address: Liuxingguo_hz@hzpharma.com.
Bioorg Chem ; 105: 104377, 2020 12.
Article in En | MEDLINE | ID: mdl-33091668
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Drug Development / Agammaglobulinaemia Tyrosine Kinase / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Chem Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Drug Development / Agammaglobulinaemia Tyrosine Kinase / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Chem Year: 2020 Document type: Article Affiliation country: Country of publication: