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Puerarin improves the bone micro-environment to inhibit OVX-induced osteoporosis via modulating SCFAs released by the gut microbiota and repairing intestinal mucosal integrity.
Li, Bo; Liu, Mingyan; Wang, Yu; Gong, Shiqiang; Yao, Weifan; Li, Wenshuai; Gao, Hua; Wei, Minjie.
Affiliation
  • Li B; School of Pharmacy, China Medical University, Shenyang, 110122, China; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, Shenyang, 110122, China.
  • Liu M; School of Pharmacy, China Medical University, Shenyang, 110122, China; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, Shenyang, 110122, China.
  • Wang Y; School of Pharmacy, China Medical University, Shenyang, 110122, China; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, Shenyang, 110122, China.
  • Gong S; School of Pharmacy, China Medical University, Shenyang, 110122, China; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, Shenyang, 110122, China.
  • Yao W; School of Pharmacy, China Medical University, Shenyang, 110122, China; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, Shenyang, 110122, China.
  • Li W; School of Pharmacy, China Medical University, Shenyang, 110122, China; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, Shenyang, 110122, China.
  • Gao H; School of Pharmacy, China Medical University, Shenyang, 110122, China; Division of Pharmacology Laboratory, National Institutes for Food and Drug Control, Beijing, 102629, China. Electronic address: huag55@163.com.
  • Wei M; School of Pharmacy, China Medical University, Shenyang, 110122, China; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, Shenyang, 110122, China. Electronic address: minjie_wei@163.com.
Biomed Pharmacother ; 132: 110923, 2020 Dec.
Article in En | MEDLINE | ID: mdl-33125971
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / Osteoporosis, Postmenopausal / Bone Remodeling / Colon / Fatty Acids, Volatile / Femur / Gastrointestinal Microbiome / Intestinal Mucosa / Isoflavones Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Biomed Pharmacother Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / Osteoporosis, Postmenopausal / Bone Remodeling / Colon / Fatty Acids, Volatile / Femur / Gastrointestinal Microbiome / Intestinal Mucosa / Isoflavones Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Biomed Pharmacother Year: 2020 Document type: Article Affiliation country: Country of publication: