[Establishment of the method for measuring upper airway critical closing pressure].
Zhonghua Jie He He Hu Xi Za Zhi
; 43(11): 953-957, 2020 Nov 12.
Article
in Zh
| MEDLINE
| ID: mdl-33137862
Objective: To establish a noninvasive method for measuring upper airway critical closing pressure (Pcrit), so as to evaluate collapsibility of the upper airway during sleep. Methods: Pcrit was determined through the use of a noninvasive positive/negative pressure (CPAP/CPNP) ventilator(with independent intellectual property rights) during stageâ
¡ of non-rapid eye movement sleep. For the direct measurement, Pcrit was the pressure below which the upper airway occluded. For the indirect measurement, nasal pressure was plotted against maximum inspiratory flow (Vimax), and linear regression was used to interpolate the pressure (i.e., Pcrit) at which zero flow occurred. Pcrit was attained from 19 subjects without obstructive sleep apnea syndrome(OSAS), and the correlation between direct and indirect measurement methods was analyzed. Results: Directly measured and indirectly measured Pcrit showed no significant difference [(-7.02±2.74 vs (-7.26±2.96) cmH2O, 1 cmH2O=0.098 kPa; t=1.667, P>0.05] and had a highly significant correlation (r=0.986, P=0.000). Bland-Altman analysis revealed that the mean between-method difference was (0.24±0.53) cmH2O, and 95% limits of agreement ranged from -0.80 to 1.27 cmH2O, and all points except one were within limits of agreement. Conclusion: Pcrit derived from the direct and indirect measurement methods does not differ, and both methods could be used for evaluating the upper airway collapsibility.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pharynx
/
Sleep Apnea, Obstructive
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
Zh
Journal:
Zhonghua Jie He He Hu Xi Za Zhi
Year:
2020
Document type:
Article
Affiliation country:
Country of publication: