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CXCL13/CXCR5 signalling is pivotal to preserve motor neurons in amyotrophic lateral sclerosis.
Trolese, Maria Chiara; Mariani, Alessandro; Terao, Mineko; de Paola, Massimiliano; Fabbrizio, Paola; Sironi, Francesca; Kurosaki, Mami; Bonanno, Silvia; Marcuzzo, Stefania; Bernasconi, Pia; Trojsi, Francesca; Aronica, Eleonora; Bendotti, Caterina; Nardo, Giovanni.
Affiliation
  • Trolese MC; Laboratory of Molecular Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy.
  • Mariani A; Laboratory of Biology of Neurodegenerative Disorders, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy.
  • Terao M; Laboratory of Molecular Biology, Department of Biochemistry and Molecular Pharmacology, Istituto di Ricerche Farmacologiche IRCCS, Via Mario Negri 2, Milan 20156, Italy.
  • de Paola M; Laboratory of Biology of Neurodegenerative Disorders, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy.
  • Fabbrizio P; Laboratory of Molecular Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy.
  • Sironi F; Laboratory of Molecular Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy.
  • Kurosaki M; Laboratory of Molecular Biology, Department of Biochemistry and Molecular Pharmacology, Istituto di Ricerche Farmacologiche IRCCS, Via Mario Negri 2, Milan 20156, Italy.
  • Bonanno S; Neurology IV-Neuroimmunology and Neuromuscular Diseases Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, Milan 20133, Italy.
  • Marcuzzo S; Neurology IV-Neuroimmunology and Neuromuscular Diseases Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, Milan 20133, Italy.
  • Bernasconi P; Neurology IV-Neuroimmunology and Neuromuscular Diseases Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, Milan 20133, Italy.
  • Trojsi F; Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", P.zza Miraglia 2, Naples 80138, Italy.
  • Aronica E; Department of Pathology, Academic Medic\\\al Centre, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, Netherlands.
  • Bendotti C; Laboratory of Molecular Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy. Electronic address: caterina.bendotti@marionegri.it.
  • Nardo G; Laboratory of Molecular Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy. Electronic address: giovanni.nardo@marionegri.it.
EBioMedicine ; 62: 103097, 2020 Dec.
Article in En | MEDLINE | ID: mdl-33161233
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Chemokine CXCL13 / Receptors, CXCR5 / Amyotrophic Lateral Sclerosis / Motor Neurons Type of study: Etiology_studies / Prognostic_studies Limits: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: EBioMedicine Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Chemokine CXCL13 / Receptors, CXCR5 / Amyotrophic Lateral Sclerosis / Motor Neurons Type of study: Etiology_studies / Prognostic_studies Limits: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: EBioMedicine Year: 2020 Document type: Article Affiliation country: Country of publication: